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AB1923

Sigma-Aldrich

Anti-Integrin αV Antibody, cytoplasmic domain

serum, Chemicon®

Synonym(e):

Vitronectin Receptor alpha Subunit, CD51 Antigen

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Antikörperform

serum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Speziesreaktivität

human

Hersteller/Markenname

Chemicon®

Methode(n)

ELISA: suitable
western blot: suitable

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Angaben zum Gen

human ... ITGAV(3685)

Spezifität

Integrin alphaV

Immunogen

Epitope: cytoplasmic domain
Synthetic peptide corresponding to amino acids 1035-1048 of human integrin alphaV. This peptide sequence is absolutely conserved in the mouse integrin alphaV sequence.

Anwendung

Research Category
Zellstruktur
Research Sub Category
Integrine
Anti-Integrin αV Antibody, cytoplasmic domain detects level of Integrin αV & has been published & validated for use in ELISA & WB.
ELISA: 1:500 (direct)

Western Blot: 1:500. Antibody detects a non-reducible 155 kDa band corresponding to integrin alphaV.

Optimal dilutions must be determined by the end user.

Physikalische Form

Whole rabbit serum. Liquid containing no preservative

Lagerung und Haltbarkeit

Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Syndecan-1 regulates alphavbeta3 and alphavbeta5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor.
Beauvais, DM; Ell, BJ; McWhorter, AR; Rapraeger, AC
The Journal of Experimental Medicine null
Qi Cui et al.
Nature communications, 7, 10637-10637 (2016-02-04)
Glioblastomas have been proposed to be maintained by highly tumorigenic glioblastoma stem cells (GSCs) that are resistant to current therapy. Therefore, targeting GSCs is critical for developing effective therapies for glioblastoma. In this study, we identify the regulatory cascade of
Laura di Blasio et al.
Journal of cell science, 128(5), 863-877 (2015-01-16)
Non-amoeboid cell migration is characterised by dynamic competition among multiple protrusions to establish new adhesion sites at the cell's leading edge. However, the mechanisms that regulate the decision to disassemble or to grow nascent adhesions are not fully understood. Here

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