8.52030

Fmoc-Thr-OH

Novabiochem^®

• Synonym(e): Fmoc-Thr-OH, N-α-Fmoc-L-threonine
• Empirische Formel (Hill-System): C₁₉H₁₉NO₅
• CAS-Nummer: 73731-37-0
• Molekulargewicht: 341.36
• UNSPSC Code: 12352209
• NACRES: NA.22
• MDL number: MFCD00792901

Eigenschaften

• Quality Segment: 200
• product line: Novabiochem^®
• assay: ≥93.0% (acidimetric), ≥98% (TLC), ≥98.0% (HPLC)
• form: powder
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• mp: 90-100 °C
• application(s): peptide synthesis
• functional group: hydroxyl
• storage temp.: 2-30°C
• SMILES string: N([C@@H]([C@@H](O)C)C(=O)[O-])C(=O)OCC1c2c(cccc2)c3c1cccc3
• InChI: 1S/C19H19NO5/c1-11(21)17(18(22)23)20-19(24)25-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16-17,21H,10H2,1H3,(H,20,24)(H,22,23)/p-1/t11-,17-/m0/s1
• InChI key: OYULCCKKLJPNPU-GTNSWQLSSA-M

Beschreibung

General description

Useful derivative for the synthesis of phosphothreonine peptides by the Fmoc SPPS global phosphorylation methodology.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS


Literature references

^[1] P. M. Fischer, et al. (1991) Int. J. Peptide Protein Res., 38, 491

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(011C)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 93.0 %
Water (K. F.): ≤ 6.00 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Other Notes

Replaces: 04-12-1060

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable