658390

AG 9 - CAS 2826-26-8 - Calbiochem

• Synonym(e): [(4-Methoxybenzylidene)malononitrile, α-Cyano-(4-methoxy)cinnamonitrile], Tyrphostin A1
• UNSPSC Code: 12352200

Eigenschaften

• assay: ≥98% (TLC)
• Quality Segment: 100
• form: solid
• color: yellow
• solubility: ethanol: 10 mg/mL, DMSO: soluble, acetic acid: soluble

Beschreibung

General description

An inactive compound that can be used as a negative control for inhibition of EGFR (IC₅₀ >1250 μM for EGFR kinase). Has been shown to inhibit IL-2 stimulated Tyk-2 phosphorylation in ConA-activated T cells.

Biochem/physiol Actions

negative control for inhibition of EGFR

Target IC<SUB>50</SUB>:>1250 μM for EGFR kinase

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Sicherheitshinweise

• Lagerklasse: 10-13 - German Storage Class 10 to 13