218739

Caspase-1 Substrate X, Fluorogenic

A fluorogenic substrate for detecting caspase-1 (ICE), caspase-4, and caspase-5 activity.

• Synonym(e): Caspase-1 Substrate X, Fluorogenic, Caspase-5 Substrate III, Fluorogenic, Ac-WEHD-AMC
• Empirische Formel (Hill-System): C₃₈H₄₀N₈O₁₁
• CAS-Nummer: 189275-74-9
• Molekulargewicht: 784.77
• MDL number: MFCD09878222
• NACRES: NA.54
• UNSPSC Code: 12352200
• Assay: ≥95% (HPLC)
• Form: lyophilized
• Storage condition: OK to freeze, desiccated, protect from light

Eigenschaften

• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: lyophilized
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, desiccated, protect from light
• solubility: DMSO: 5 mg/mL
• fluorescence: λ_ex 365–380 nm, λ_em 430–460 nm
• shipped in: ambient
• storage temp.: −20°C

Beschreibung

General description

A fluorogenic substrate for detecting caspase-1 (ICE) (excitation maximum: ~365-380 nm; emission maximum: ~430-460 nm).

Biochem/physiol Actions

Cell permeable: no

Product does not compete with ATP.

Reversible: no

Other Notes

Ac-Trp-Glu-His-Asp-AMC

Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable