218739

Caspase-1 Substrate X, Fluorogenic

A fluorogenic substrate for detecting caspase-1 (ICE), caspase-4, and caspase-5 activity.

• Synonym(e): Caspase-1 Substrate X, Fluorogenic, Caspase-5 Substrate III, Fluorogenic, Ac-WEHD-AMC
• Empirische Formel (Hill-System): C₃₈H₄₀N₈O₁₁
• CAS-Nummer: 189275-74-9
• Molekulargewicht: 784.77
• UNSPSC-Code: 12352200
• NACRES: NA.54

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥95% (HPLC)
• Form: lyophilized
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; desiccated; protect from light
• Löslichkeit: DMSO: 5 mg/mL
• Fluoreszenz: λ_ex 365–380 nm; λ_em 430–460 nm
• Versandbedingung: ambient
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

A fluorogenic substrate for detecting caspase-1 (ICE) (excitation maximum: ~365-380 nm; emission maximum: ~430-460 nm).

A fluorogenic substrate for detecting caspase-1 (ICE), caspase-4, and caspase-5 activity.

Biochem./physiol. Wirkung

Cell permeable: no

Product does not compete with ATP.

Reversible: no

Warnhinweis

Toxicity: Standard Handling (A)

Sequenz

Ac-Trp-Glu-His-Asp-AMC

Sonstige Hinweise

Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable