M-020

S(+)-Methamphetamin -Lösung

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Synonym(e): Dextro-Methamphetamin
• Empirische Formel (Hill-System): C₁₀H₁₅N
• CAS-Nummer: 537-46-2
• Molekulargewicht: 149.23
• MDL-Nummer: MFCD00079140
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329817739
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material
• Form: liquid
• Leistungsmerkmale: Snap-N-Spike^®/Snap-N-Shoot^®
• Verpackung: ampule of 1 mL
• Hersteller/Markenname: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)
• Konzentration: 1.0 mg/mL in methanol
• Methode(n): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Anwendung(en): forensics and toxicology
• Format: single component solution
• Lagertemp.: 2-8°C
• SMILES String: CN[C@@H](C)Cc1ccccc1
• InChI: 1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3/t9-/m0/s1
• InChIKey: MYWUZJCMWCOHBA-VIFPVBQESA-N
• Angaben zum Gen: human ... SLC6A2(6530) , SLC6A3(6531) , SLC6A4(6532)

Beschreibung

Allgemeine Beschreibung

Methamphetamin ist eine psychostimulierende Droge aus der Stoffgruppe der Phenethylamine und Amphetamine. Diese umgangssprachlich auch als „Meth“, „Ice“ und „Crystal“ bekannte Snap-N-Spike^®-Referenzlösung eignet sich für den Einsatz in LC-MS- oder GC-MS-Anwendungen zum Beispiel in der klinischen Toxikologie, bei Tests im Sport und in der forensischen Analytik oder der Urin-Drogenkontrolle. Das rechtsdrehende Isomer von Methamphetamin wird unter dem Handelsnamen Desoxyn^® zur Behandlung von ADHS und Adipositas verkauft.

Anwendung

• Pharmacokinetic Studies of S(+)-Methamphetamine: A comprehensive study assessing the pharmacokinetic profile of S(+)-Methamphetamine highlighted its rapid absorption and metabolism, offering critical insights into its therapeutic potential and challenges in drug abuse scenarios. This research aids in optimizing dosing regimens and understanding the drug′s behavior in biological systems, essential for both clinical applications and forensic investigations (Rushton et al., 2024).


• Pharmaceutical Applications of S(+)-Methamphetamine: Research on S(+)-Methamphetamine′s role in neurochemical processes explored its effects on neurotransmitter systems, particularly focusing on its potential therapeutic applications for attention deficit hyperactivity disorder (ADHD) and weight loss. Studies like these inform drug design and repurposing strategies, helping to mitigate abuse risks while harnessing pharmacological benefits (Pardo et al., 2024).


• Drug Metabolism and Enantiomeric Analysis: Investigations into the metabolism of S(+)-Methamphetamine have provided detailed insights into its biotransformation pathways, crucial for developing antidotes and treatment strategies for overdose cases. This research also enhances the understanding of enantiomeric differences in drug activity, supporting the development of more targeted and effective therapeutic agents (Liut et al., 2024).


• Clinical Trials and Neurological Research: Systematic reviews of clinical trials involving S(+)-Methamphetamine have elucidated its complex pharmacodynamics and associated behavioral effects. This information is vital for neuroscientists and pharmacologists working to develop safer and more effective CNS stimulants with fewer side effects and lower abuse potential (Barkholtz et al., 2023).

Rechtliche Hinweise

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Desoxyn is a registered trademark of Abbott Laboratories Corp.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS02,GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H225,H301 + H311 + H331,H370
• P-Sätze: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Zielorgane: Eyes
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 1
• Flammpunkt (°F): 49.5 °F - closed cup
• Flammpunkt (°C): 9.7 °C - closed cup