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Merck

TNFRSF18

tumor necrosis factor receptor superfamily, member 18

Synonyme:
AITR, CD357, GITR, GITR-D
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(8784) Summary: This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
  • Mouse(21936) tumor necrosis factor receptor superfamily, member 18
  • Rat(500598) tumor necrosis factor receptor superfamily, member 18
  • sheep(101108672) tumor necrosis factor receptor superfamily, member 18
  • domestic cat(101083251) tumor necrosis factor receptor superfamily, member 18
  • domestic guinea pig(100715459) tumor necrosis factor receptor superfamily, member 18
  • naked mole-rat(101715065) tumor necrosis factor receptor superfamily, member 18
  • cow(516256) tumor necrosis factor receptor superfamily, member 18
  • dog(606971) tumor necrosis factor receptor superfamily, member 18
  • Zebrafish(571217) tumor necrosis factor receptor superfamily, member 18
  • chicken(419424) tumor necrosis factor receptor superfamily, member 18

Custom & Knockdown Gene Products

ELISA

Produktnummer
Beschreibung
Spezies
Human GITR / TNFRSF18 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Spezies
human
Mouse Tnfrsf18 ELISA Kit, ,
Spezies
mouse
Human GITR / TNFRSF18 ELISA Kit, for cell and tissue lysates,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-TNFRSF18 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL7787, purified immunoglobulin, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
western blot
Anti-TNFRSF18 (soluble form) Antibody, clone T10P2H9*B9, clone T10P2H9*B9, from mouse,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-hGITR Antibody, clone 108-17, clone 108-17, from mouse,
Speziesreaktivität
human, mouse, rat
Anwendung
western blot

Proteins

Produktnummer
Beschreibung
Spezies
CD40, FC Fusion, recombinant, expressed in HEK 293 cells,
Spezies
human
GITR (CD357), FC Fusion, recombinant, expressed in HEK 293 cells,
Spezies
human
GITR (CD357), FC Fusion, Biotin Labeled, recombinant, expressed in HEK 293 cells,
Spezies
human