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RPS6KB1

ribosomal protein S6 kinase, 70kDa, polypeptide 1

Synonyme:
PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(6198) Summary: This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]
  • Mouse(72508) ribosomal protein S6 kinase, polypeptide 1
  • Rat(83840) ribosomal protein S6 kinase, polypeptide 1
  • cow(404181) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • sheep(101107371) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • chicken(417637) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • Domestic Rabbit(100009260) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • domestic cat(101092561) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • Horse(100057481) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • dog(480580) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • domestic guinea pig(100727216) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • naked mole-rat(101724077) ribosomal protein S6 kinase, 70kDa, polypeptide 1

Custom & Knockdown Gene Products

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-phospho-p70 S6 Kinase (Thr389) Antibody, clone 10G7.1, clone 10G7.1, from mouse,
Speziesreaktivität
human, mouse
Anwendung
immunocytochemistry
western blot
Anti-Phospho-p70-S6-Kinase(Thr389)-Antikörper, from rabbit, purified by affinity chromatography,
Speziesreaktivität
bovine, chicken, human, mouse, rat, zebrafish
Anwendung
inhibition assay
western blot
Anti-P70 S6K antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
immunohistochemistry

western blot
Anti-phospho-p70 S6 Kinase (pThr389) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-phospho-p70 S6 Kinase (pThr389/412) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
PF-4708671, ≥98% (HPLC),
Spezies
human, mouse, rat

Proteins

Produktnummer
Beschreibung
Spezies
p70-S6-Kinaseprotein, aktiv, 10 µg, Active, N-terminal His6-tagged, recombinant amino acids 1-421 of human p70 S6 kinase, for use in Kinase Assays.,
Spezies
human
p70S6K, active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human
p70S6K active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE),
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human RPS6KB1,
Spezies
human