Direkt zum Inhalt
Merck

RASGRP2

RAS guanyl releasing protein 2 (calcium and DAG-regulated)

Synonyme:
CALDAG-GEFI, CDC25L
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(10235) Summary: The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(19395) RAS, guanyl releasing protein 2
  • Rat(361714) RAS guanyl releasing protein 2 (calcium and DAG-regulated)
  • sheep(101104023) RAS guanyl releasing protein 2 (calcium and DAG-regulated)
  • dog(612101) RAS guanyl releasing protein 2 (calcium and DAG-regulated)
  • domestic cat(101094450) RAS guanyl releasing protein 2 (calcium and DAG-regulated)
  • Horse(100055959) RAS guanyl releasing protein 2 (calcium and DAG-regulated)
  • Zebrafish(557063) RAS guanyl releasing protein 2 (calcium and DAG-regulated)
  • naked mole-rat(101714183) RAS guanyl releasing protein 2 (calcium and DAG-regulated)
  • domestic guinea pig(100722152) RAS guanyl releasing protein 2 (calcium and DAG-regulated)
  • Domestic Rabbit(100328903) RAS guanyl releasing protein 2 (calcium and DAG-regulated)
  • cow(512056) RAS guanyl releasing protein 2 (calcium and DAG-regulated)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-phospho RasGRP2 (Ser554), from rabbit,
Speziesreaktivität
baboon, human, monkey, mouse, porcine, rabbit, rat
Anwendung
western blot
Anti-RASGRP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-phospho RasGRP2 (Ser586), from rabbit,
Speziesreaktivität
monkey, mouse, rat
Anwendung
western blot
Anti-RASGRP2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
western blot
Anti-phospho RasGRP2 (Ser116/Ser117), from rabbit,
Speziesreaktivität
monkey, mouse, rat
Anwendung
immunofluorescence
western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Rasgrp2,
Spezies
mouse
MISSION® esiRNA, targeting human RASGRP2,
Spezies
human