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MMP8

matrix metallopeptidase 8 (neutrophil collagenase)

Synonyme:
CLG1, HNC, MMP-8, PMNL-CL
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(4317) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
  • Mouse(17394) matrix metallopeptidase 8
  • Rat(63849) matrix metallopeptidase 8
  • domestic guinea pig(100724670) matrix metallopeptidase 8 (neutrophil collagenase)
  • naked mole-rat(101716969) matrix metallopeptidase 8 (neutrophil collagenase)
  • sheep(101120601) matrix metallopeptidase 8 (neutrophil collagenase)
  • domestic cat(101080995) matrix metallopeptidase 8 (neutrophil collagenase)
  • Horse(100069005) matrix metallopeptidase 8 (neutrophil collagenase)
  • cow(100336575) matrix metallopeptidase 8 (neutrophil collagenase)
  • dog(489429) matrix metallopeptidase 8 (neutrophil collagenase)

Custom & Knockdown Gene Products

ELISA

Produktnummer
Beschreibung
Spezies
Human MMP-8 ELISA Kit, for serum, plasma, conditioned medium, urine,
Spezies
human
Rat MMP-8 ELISA Kit, for serum, plasma, cell culture supernatant,
Spezies
mouse

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-MMP8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-MMP8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-Mmp8 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Doxycycline monohydrate, ,
Spezies
human
Doxycycline Monohydrate, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
αα-Sexithiophen, ,
Spezies
human, rat
Marimastat, ≥98% (HPLC),
Spezies
human, rat, mouse
CP-101537, ≥98% (HPLC),
Spezies
human, rat, mouse

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human MMP8,
Spezies
human