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LONP1

lon peptidase 1, mitochondrial

Synonyme:
LON, LONP, LonHS, PIM1, PRSS15, hLON
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(9361) Summary: This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013]
  • Mouse(74142) lon peptidase 1, mitochondrial
  • Rat(170916) lon peptidase 1, mitochondrial
  • domestic guinea pig(100717869) lon peptidase 1, mitochondrial
  • domestic cat(101093417) lon peptidase 1, mitochondrial
  • chicken(768942) lon peptidase 1, mitochondrial
  • Zebrafish(563257) lon peptidase 1, mitochondrial
  • naked mole-rat(101710908) lon peptidase 1, mitochondrial
  • dog(611425) lon peptidase 1, mitochondrial
  • sheep(101109965) lon peptidase 1, mitochondrial
  • cow(510796) lon peptidase 1, mitochondrial

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-LONP1 antibody produced in rabbit, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
immunohistochemistry

western blot
Anti-LONP1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human, mouse
Anwendung
immunofluorescence
western blot
Anti-LONP1 Antibody, clone 1I18, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human, mouse, rat
Anwendung
immunocytochemistry
immunohistochemistry

western blot
Monoclonal Anti-PRSS15 antibody produced in mouse, clone 3B2, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human LONP1,
Spezies
human
MISSION® esiRNA, targeting mouse Lonp1,
Spezies
mouse