KRT86
keratin 86
Synonyme:
HB6, Hb1, KRTHB1, KRTHB6, MNX, hHb6
Spezies:
Human KRT86 (3892), Mouse Krt86 (16679), Rat Krt86 (407760), domestic cat KRT86 (101096995), dog KRT86 (486530), Horse KRT86 (100062959), cow KRT86 (535232), sheep KRT86 (101112469), naked mole-rat Krt86 (101701592), domestic guinea pig Krt86 (100714698)
UniProtKB-ID:
Gen-ID:
- Human(3892) Summary: The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB3, is found primarily in the hair cortex. Mutations in this gene and KRTHB1 have been observed in patients with a rare dominant hair disease, monilethrix. [provided by RefSeq, Jul 2008]
- Mouse(16679) keratin 86
- Rat(407760) keratin 86
- domestic cat(101096995) keratin 86
- dog(486530) keratin 86
- Horse(100062959) keratin 86
- cow(535232) keratin 86
- sheep(101112469) keratin 86
- naked mole-rat(101701592) keratin 86
- domestic guinea pig(100714698) keratin 86
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