HCST
hematopoietic cell signal transducer
Synonyme:
DAP10, KAP10, PIK3AP
Spezies:
Human HCST (10870), Mouse Hcst (23900), Rat Hcst (474146), sheep HCST (101107544), dog HCST (612627), domestic cat HCST (101097286), cow HCST (767892), Zebrafish hcst (100101460)
UniProtKB-ID:
Gen-ID:
- Human(10870) Summary: This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(23900) hematopoietic cell signal transducer
- Rat(474146) hematopoietic cell signal transducer
- sheep(101107544) hematopoietic cell signal transducer
- dog(612627) hematopoietic cell signal transducer
- domestic cat(101097286) hematopoietic cell signal transducer
- cow(767892) hematopoietic cell signal transducer
- Zebrafish(100101460) hematopoietic cell signal transducer
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