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CCDC88C

coiled-coil domain containing 88C

Synonyme:
DAPLE, HKRP2, KIAA1509
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(440193) Summary: This gene encodes a ubiquitously expressed coiled-coil domain-containing protein that interacts with the dishevelled protein and is a negative regulator of the Wnt signalling pathway. The protein encoded by this gene has a PDZ-domain binding motif in its C-terminus with which it interacts with the dishevelled protein. Dishevelled is a scaffold protein involved in the regulation of the Wnt signaling pathway. The Wnt signaling pathway plays an important role in embryonic development, tissue maintenance, and cancer progression. Mutations in this gene cause autosomal recessive, primary non-syndromic congenital hydrocephalus; a condition characterized by excessive accumulation of cerebrospinal fluid in the ventricles of the brain. [provided by RefSeq, Jan 2013]
  • Mouse(68339) coiled-coil domain containing 88C
  • Rat(362770) coiled-coil domain containing 88C
  • domestic cat(101086153) coiled-coil domain containing 88C
  • chicken(423410) coiled-coil domain containing 88C
  • domestic guinea pig(100726024) coiled-coil domain containing 88C
  • naked mole-rat(101711088) coiled-coil domain containing 88C
  • sheep(101112005) coiled-coil domain containing 88C
  • Domestic Rabbit(100349859) coiled-coil domain containing 88C
  • cow(515039) coiled-coil domain containing 88C
  • dog(480418) coiled-coil domain containing 88C

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-CCDC88C antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human CCDC88C,
Spezies
human