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Merck

CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

Synonyme:
CACNA1HB, Cav3.2, ECA6, EIG6
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(8912) Summary: This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE). [provided by RefSeq, Jul 2008]
  • Mouse(58226) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • Rat(114862) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • dog(403533) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • domestic cat(101090071) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • domestic guinea pig(100720102) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • naked mole-rat(101712631) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • chicken(416526) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • cow(282412) calcium channel, voltage-dependent, T type, alpha 1H subunit

Custom & Knockdown Gene Products

Small Molecule - Allosteric Modulator

Produktnummer
Beschreibung
Spezies
Gabapentin, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
Gabapentin -Lösung, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
Pregabalin, European Pharmacopoeia (EP) Reference Standard,
Spezies
human
Gabapentin -Lösung, 10 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Anti-Calcium Channel CaV3.2 (α1H) in Kaninchen hergestellte Antikörper, affinity isolated antibody, lyophilized powder,
Speziesreaktivität
rat
Anwendung
western blot
Anti-CACNA1H antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
Anti-CACNA1H antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
western blot
Anti-Cav3.2 Antibody, Chemicon®, from rabbit,
Speziesreaktivität
rat
Anwendung
western blot

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
Ethosuximid, ,
Spezies
human
Ethosuximid, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
Ethosuximid, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Ethosuximid, European Pharmacopoeia (EP) Reference Standard,
Spezies
human
Trimethadion, European Pharmacopoeia (EP) Reference Standard,
Spezies
human