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Merck

CACNA1B

calcium channel, voltage-dependent, N type, alpha 1B subunit

Synonyme:
BIII, CACNL1A5, CACNN, Cav2.2
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(774) Summary: The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
  • Mouse(12287) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • Rat(257648) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • cow(282410) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • chicken(374169) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • dog(480660) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • Domestic Rabbit(100008979) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • naked mole-rat(101697609) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • domestic guinea pig(100735203) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • domestic cat(101087362) calcium channel, voltage-dependent, N type, alpha 1B subunit

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Small Molecule - Allosteric Modulator

Produktnummer
Beschreibung
Spezies
Levetiracetam, ≥98% (HPLC),
Spezies
human
Levetiracetam, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
Levetiracetam, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Levetiracetam, European Pharmacopoeia (EP) Reference Standard,
Spezies
human
Gabapentin, United States Pharmacopeia (USP) Reference Standard,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Cav2.2 Antibody, Chemicon®, from rabbit,
Speziesreaktivität
rat
Anwendung
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-CACNA1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-CACNA1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
Anti-Calcium Channel (α1B Subunit) (N-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Speziesreaktivität
mouse, rat
Anwendung
immunocytochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
Levetiracetam, ≥98% (HPLC),
Spezies
human
Levetiracetam, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
Levetiracetam, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Levetiracetam, European Pharmacopoeia (EP) Reference Standard,
Spezies
human
ω-Conotoxin GVIA, ≥97% (HPLC),
Spezies
mouse, rat, human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Cacna1b,
Spezies
mouse
MISSION® esiRNA, targeting human CACNA1B,
Spezies
human