APLP2
amyloid beta (A4) precursor-like protein 2
Synonyme:
APLP-2, APPH, APPL2, CDEBP
Spezies:
Human APLP2 (334), Mouse Aplp2 (11804), Rat Aplp2 (64312), naked mole-rat Aplp2 (101696833), Horse APLP2 (100068170), Horse APLP2 (100072668), domestic cat APLP2 (101095518), sheep APLP2 (101119774), domestic guinea pig Aplp2 (100713756), Domestic Rabbit APLP2 (100358231) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(334) Summary: This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
- Mouse(11804) amyloid beta (A4) precursor-like protein 2
- Rat(64312) amyloid beta (A4) precursor-like protein 2
- naked mole-rat(101696833) amyloid beta (A4) precursor-like protein 2
- Horse(100068170) amyloid beta (A4) precursor-like protein 2
- Horse(100072668) amyloid beta (A4) precursor-like protein 2
- domestic cat(101095518) amyloid beta (A4) precursor-like protein 2
- sheep(101119774) amyloid beta (A4) precursor-like protein 2
- domestic guinea pig(100713756) amyloid beta (A4) precursor-like protein 2
- Domestic Rabbit(100358231) amyloid beta (A4) precursor-like protein 2
- chicken(419727) amyloid beta (A4) precursor-like protein 2
- Zebrafish(796801) amyloid beta (A4) precursor-like protein 2
- cow(785005) amyloid beta (A4) precursor-like protein 2
- dog(479393) amyloid beta (A4) precursor-like protein 2
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-APLP2 antibody produced in mouse, clone 4B5, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
Anti-APLP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-APLP2 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
western blot
western blot
Anti-APLP2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
western blot