Poloxamer 188 in Protein Formulation

WEBINAR

Poloxamer 188 finds wide application in the development and manufacturing process of pharmaceutical drug products. In liquid protein formulations, Poloxamer 188 (PLX188) is added to stabilize proteins against mechanical stress, ensuring the desired therapeutic activity and safety of biologics. In cell culture media, PLX188 is added as shear stress protector to prevent cell damage during the cultivation in bioreactor and guarantee optimal cell growth.

We will show how the performance of PLX188 in these applications can be affected by variations in molecular weight or hydrophobicity, observed among different batches or products. 

In this webinar, you will learn:

• the function of Poloxamer 188 as stabilizer in biopharmaceutical products 
• the function of Poloxamer 188 as shear stress protector in cell culture
• the impact of material attributes on the different applications of Poloxamer 188 in liquid protein formulation and in cell culture media