1612652

Simethicone

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): α-(Trimethylsilyl)-ω-methylpoly[oxy(dimethylsilylene)] mixture with silicon dioxide, Antifoam A, Antifoam AF
• CAS Number: 8050-81-5
• MDL number: MFCD00134211
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• agency: USP
• API family: simethicone
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: [Si](O[Si](C)(C)C)(OC)(C)C.[Si](=O)=O
• InChI: 1S/C6H18O2Si2.O2Si/c1-7-10(5,6)8-9(2,3)4;1-3-2/h1-6H3;
• InChI key: AMTWCFIAVKBGOD-UHFFFAOYSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Simethicone comprises a combination of linear siloxane polymers that are fully methylated and consist of repeating units represented by the formula [–(CH₃)₂SiO–]n. The polymer is further stabilized using trimethylsiloxy end-blocking units denoted by the formula [(CH₃)₃SiO–], along with silicon dioxide.

Application

Simethicone USP reference standard suitable for use in specified USP compendial tests and assays.

Also used to prepare standard solutions for impurity analysis in Simethicone using the IR technique according to the United States Pharmacopeia (USP) monograph.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable