UC205

Dextrorphan

NMDA glutamate receptor antagonist, solid

• Synonym(s): (+)-3-Hydroxy-17-methylmorphinan, 1,3,4,9,10,10a-Hexahydro-6-hydroxy-2H-10,4a-(iminoethano)-11-methylphenanthrene
• Empirical Formula (Hill Notation): C₁₇H₂₃NO
• CAS Number: 125-73-5
• Molecular Weight: 257.37
• NACRES: NA.77
• PubChem Substance ID: 24724648
• UNSPSC Code: 12161501
• EC Number: 204-754-3
• MDL number: MFCD00864199
• Form: solid
• Quality level: 200

Properties

• Product Name: Dextrorphan,
• form: solid
• Quality Level: 200
• optical activity: [α]/D ≥+54°
• color: white to off-white
• mp: ≥195 °C
• solubility: saline: soluble(lit.)
• storage temp.: 2-8°C
• SMILES string: CN1CC[C@@]23CCCC[C@@H]2[C@@H]1Cc4ccc(O)cc34
• InChI: 1S/C17H23NO/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17/h5-6,11,14,16,19H,2-4,7-10H2,1H3/t14-,16+,17+/m1/s1
• InChI key: JAQUASYNZVUNQP-PVAVHDDUSA-N
• Gene Information: human ... GRIN2A(2903) ; rat ... Grin2a(24409)

Description

Application

Dextrorphan has been studies as an N-methyl-D-aspartate (NMDA) receptor antagonist in Xenopus oocytes and hippocampal neuron cultures.

CYP2D6 O-Demethyl metabolite of dextromethorphan

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Preparation Note

Dextrorphan is soluble in water.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves