The purity of this material is indicated by the dye content. The minimum dye content of this product is 65%. A brief review of recent lots indicates that 85 - 90% dye content is typical. Please see the link below to review additional information available in the product datasheet:
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/543/093/t3516pis.pdf
T3516
Thioflavin T
Powder
Synonym(s):
Basic Yellow 1, Thioflavine T
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About This Item
Empirical Formula (Hill Notation):
C17H19ClN2S
CAS Number:
Molecular Weight:
318.86
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
219-228-9
MDL number:
Beilstein/REAXYS Number:
3922452
Colour Index Number:
49005
Pricing and availability is not currently available.
Product Name
Thioflavin T, used as stain for amyloid
Quality Segment
form
powder
composition
Dye content, ≥65%
solubility
methanol: 1 mg/mL
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
[Cl-].CN(C)c1ccc(cc1)-c2sc3cc(C)ccc3[n+]2C
InChI
1S/C17H19N2S.ClH/c1-12-5-10-15-16(11-12)20-17(19(15)4)13-6-8-14(9-7-13)18(2)3;/h5-11H,1-4H3;1H/q+1;/p-1
InChI key
JADVWWSKYZXRGX-UHFFFAOYSA-M
General description
Application
Thioflavin T has been used to identify the presence of amyloid fibrils in samples.
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This Item | |||
|---|---|---|---|
| description used as stain for amyloid | description used as fluorescent tracer | description special for flagella, certified | description Technical grade |
| solubility methanol: 1 mg/mL | solubility H2O: 1 mg/mL | solubility H2O: 1 mg/mL | solubility H2O: 1 mg/mL |
| form powder | form powder | form powder | form powder |
| application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing |
| storage temp. room temp | storage temp. room temp | storage temp. room temp | storage temp. room temp |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| composition Dye content, ≥65% | composition - | composition pararosaniline acetate, 3 parts , pararosaniline chloride, 1 part | composition Dye content, ~80% |
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Signal Word
Danger
Hazard Codes
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Sens. 1
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, type N95 (US)
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How do you reconsititute the powder?
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As described in the product data sheet, the product is soluble in methanol at 1mg/mL (0.1% w/v).
Please see the product data sheet for additional solubility and handling recommendations: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/543/093/t3516pis.pdfHelpful?
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