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SML3485

PFI-7 hydrochloride

≥98% (HPLC)

Synonym(s):

N-((1s,4s)-4-(1H-Benzo[d]imidazol-2-yl)cyclohexyl)-2-((1H-indol-2-yl)methylamino)acetamide hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C24H27N5O · xHCl
Molecular Weight:
401.50 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.28
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(CNCC1=CC2=C(N1)C=CC=C2)N[C@@H]3CC[C@@H](CC3)C4=NC5=C(N4)C=CC=C5

InChI key

HLHNFJNSQZZUNW-MAEOIBBWSA-N

Biochem/physiol Actions

PFI-7 is a high affinity E3 ligase GID4 probe (KD = 0.08 μM by SPR) that competes against cellular degrons for full-length GID4 binding with high potency (EC50 = 0.6 μM by cell-based NanoBRET).

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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