SML1649

Urolithin B

≥95% (HPLC), antiproliferative agent, powder

• Synonym(s): 3-Hydroxy-6H-benzo[c]chromen-6-one
• Empirical Formula (Hill Notation): C₁₃H₈O₃
• CAS Number: 1139-83-9
• Molecular Weight: 212.20
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825989
• NACRES: NA.77
• MDL number: MFCD00034338
• Assay: ≥95% (HPLC)
• Form: powder

Properties

• Product Name: Urolithin B, ≥95% (HPLC)
• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 5 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: [o]1c2c(c3c([c]1=O)cccc3)ccc(c2)O
• InChI: 1S/C13H8O3/c14-8-5-6-10-9-3-1-2-4-11(9)13(15)16-12(10)7-8/h1-7,14H
• InChI key: WXUQMTRHPNOXBV-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Urolithin B is a natural product with antiproliferative and antioxidant activity.

Urolithin B is a natural product with antiproliferative and antioxidant activity. Urolithin B is formed by metabolism from polyphenols found in some nuts and fruits, particularly pomegranates. Urolithin B has been shown to cross the blood brain barrier, and may have neuroprotective effects against Alzheimer′s Disease.

It decreases protein degradation and induces muscle hypertrophy. Urolithin B inhibits the activity of aromatase, an enzyme that interconverts estrogen and testosterone.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319
• pcodes: P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable