Our labs have validated the solubility of SML1468, Dienogest, at a concentration of 5 mg/mL in warmed DMSO.
As we offer many different options for Progesterone, it will be necessary to specify the catalog number before we can provide a recommendation.
SML1468
Dienogest
≥98% (HPLC)
Synonym(s):
(17a)-17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile, 17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile, 17-cyanomethyl-17-hydroxy-estra-4,9-dien-3-one
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About This Item
Empirical Formula (Hill Notation):
C20H25NO2
CAS Number:
Molecular Weight:
311.42
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Pricing and availability is not currently available.
Quality Segment
assay
≥98% (HPLC)
form
powder
optical activity
[α]/D -305 to -325°, c = 1 in dichloromethane
color
white to beige
solubility
DMSO: 5 mg/mL, clear (warmed)
storage temp.
2-8°C
SMILES string
O[C@@]1(CC#N)CC[C@@]2([H])[C@]3([H])CCC4=CC(CCC4=C3CC[C@@]21C)=O
InChI
1S/C20H25NO2/c1-19-8-6-16-15-5-3-14(22)12-13(15)2-4-17(16)18(19)7-9-20(19,23)10-11-21/h12,17-18,23H,2-10H2,1H3/t17-,18+,19+,20-/m1/s1
InChI key
AZFLJNIPTRTECV-FUMNGEBKSA-N
Biochem/physiol Actions
Dienogest is a fourth-generation progestin, an orally active synthetic progestogen with approximately 10% of the relative affinity of progesterone, but has a very potent progestagenic effect in the endometrium with some antiandrogenic activity and without any androgenic, glucocorticoid or mineralocorticoid effects. It has been used alone or in combination as a contraceptive and to treat uterine fibroids. Dienogest inhibits ovulation primarily through peripheral action rather than by central action on gonadotrophin secretion.
Dienogest is an orally active synthetic progestogen
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This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description European Pharmacopoeia (EP) Reference Standard | description European Pharmacopoeia (EP) Reference Standard | description ≥97% (HPLC) |
| form powder | form - | form - | form powder |
| assay ≥98% (HPLC) | assay - | assay - | assay ≥97% (HPLC) |
| Quality Level 100 | Quality Level - | Quality Level - | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. room temp |
| solubility DMSO: 5 mg/mL, clear (warmed) | solubility - | solubility - | solubility DMSO: 20 mg/mL, clear |
| color white to beige | color - | color - | color white to beige |
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Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Repr. 2
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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dienogestとprogesteroneはそれぞれ、DMSOとETOHに溶かすのがよいのでしょうか？
1 answer-
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