SML1285

Febuxostat

98.5-102.0% (dry basis), powder, xanthine oxidase inhibitor

• Synonym(s): 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid, Adenuric, Atenuri, Uloric
• Empirical Formula (Hill Notation): C₁₆H₁₆N₂O₃S
• CAS Number: 144060-53-7
• Molecular Weight: 316.37
• UNSPSC Code: 51111800
• PubChem Substance ID: 329825764
• NACRES: NA.77
• MDL number: MFCD00871598
• Assay: 98.5-102.0%
• Form: powder

Properties

• Product Name: Febuxostat, 98.5-102.0%
• Quality Segment: 200
• assay: 98.5-102.0%
• form: powder
• storage temp.: 2-8°C
• SMILES string: CC(C)COC1=C(C#N)C=C(C2=NC(C)=C(C(O)=O)S2)C=C1
• InChI: 1S/C16H16N2O3S/c1-9(2)8-21-13-5-4-11(6-12(13)7-17)15-18-10(3)14(22-15)16(19)20/h4-6,9H,8H2,1-3H3,(H,19,20)
• InChI key: BQSJTQLCZDPROO-UHFFFAOYSA-N

Description

General description

Febuxostat is a potent, non-purine compound, which inhibits the expression of cytokines/chemokines. It has also been reported to inhibit LPS-induced TNF-α, VCAM-1, MMP9 and MCP-1 expression.

Biochem/physiol Actions

Febuxostat is a potent non-purine xanithine oxidase inhibitor.

Febuxostat is a potent non-purine xanithine oxidase inhibitor. Febuxostat is used in urate lowering therapies (ULTs) for the treatment of gout.

Disclaimer

Freely soluble in N,N-dimethyl formamide, Soluble in dimethyl sulfoxide, sparingly soluble in ethanol or trichloromethane, slightly soluble in methanol, practically insoluble in water

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable