This product is a mixture of Oleic acid and Cyclodextrin. Each gram of powder will include a minimum of 28 mg Oleic acid. The product is sold by Oleic acid content. At the minimum Oleic acid content, the 10 mg package size would contain a total of 357 mg of powder. The Oleic acid content is lot specific. Please see the link below to review a sample or lot specific Certificate of Analysis:
https://www.sigmaaldrich.com/product/sigma/o1257#product-documentation
O1257
Oleic Acid-Water Soluble
powder, BioReagent, suitable for cell culture
Synonym(s):
Oleic Acid–Cyclodextrin Complex
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About This Item
Pricing and availability is not currently available.
biological source
synthetic (organic)
Quality Segment
product line
BioReagent
form
powder
composition
Oleic acid, ~30 mg/g (balance methyl-β-cyclodextrin)
technique(s)
cell culture | mammalian: suitable
solubility
H2O: 50 mg/mL, clear to slightly hazy
storage temp.
−20°C
SMILES string
CCCCCCCC\C=C/CCCCCCCC(O)=O
InChI
1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9-
InChI key
ZQPPMHVWECSIRJ-KTKRTIGZSA-N
Gene Information
human ... SOAT1(6646), SOAT2(8435)
Application
Oleic Acid-Water Soluble has been used:
- to prepare the FFAs (free fatty acids) mixture for cell treatment
- to investigate its effect on the solute carrier family 2 member 4 (SLC2A4)/GLUT4 expression in L6 muscle cells and as potential transcriptional regulators
- in the preparation of fatting media for the induction of in vitro steatosis in primary human hepatocytes
Other Notes
Methyl-β-cylodextran binding improves the solubility and delivery of Oleic acid in culture media.
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This Item | |||
|---|---|---|---|
| technique(s) cell culture | mammalian: suitable | technique(s) - | technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable |
| biological source synthetic (organic) | biological source semisynthetic | biological source bovine | biological source synthetic (organic) |
| form powder | form powder | form liquid | form solid |
| storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. room temp |
| solubility H2O: 50 mg/mL, clear to slightly hazy | solubility - | solubility - | solubility H2O: 25 mg/mL, clear to slightly hazy |
| Quality Level 200 | Quality Level 200 | Quality Level 300 | Quality Level 200 |
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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Could you please clarify whether the entire 10mg of the compound is oleic acid, or does the 10mg compound actually contain 377ug (37.7mg/g * 10mg) of oleic acid, considering the specified concentration?
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