M9917

Mannan−Agarose

saline suspension

• Synonym(s): Mannan Binding Protein Agarose
• UNSPSC Code: 23151817
• NACRES: NA.56
• MDL number: MFCD00213010

Properties

• biological source: plant
• Quality Segment: 200
• form: saline suspension
• technique(s): affinity chromatography: suitable
• matrix: cross-linked 4% beaded agarose
• matrix activation: cyanogen bromide
• matrix attachment: hydroxyl
• matrix spacer: 1 atom
• capacity: ≥30 mg/mL binding capacity (concanavalin A)
• suitability: suitable for chromatography
• storage temp.: 2-8°C

Description

Application

Mannan-agarose is used in protein chromatography, affinity chromatography and carbohydrate matrices. Mannan-agarose has been used in studies assessing poly(ADP-ribosyl)ation of mannose-binding lectin out of human kidney cells and to inform mannose-associated serine protease (MASP) activated components of the coagulation system. Mannan-agarose has also been used to study the innate immunity and resistance to Aeromonas salmonicida exhibited by the sea lamprey (Petromyzon marinus), a parasitic cartilaginous fish of the North American Great Lakes and a predator of many bony fish species of commercial importance to the fishing industry. Mannan-Agarose has been used to deplete rabbit anti-mannose-binding lectin (MBL) polyclonal antiserum of anti-mannan antibodies.

Physical form

Suspension in 1.0 M NaCl, 10 mM imidazole containing preservative

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable