M2910

[D-Trp⁷, Ala⁸, D-Phe¹⁰]-α-Melanocyte Stimulating Hormone Amide Fragment 6-11

≥97% (HPLC)

• Synonym(s): GHRP-6
• Empirical Formula (Hill Notation): C₄₆H₅₆N₁₂O₆
• CAS Number: 87616-84-0
• Molecular Weight: 873.01
• MDL number: MFCD00872694
• UNSPSC Code: 51111800
• PubChem Substance ID: 24896777
• NACRES: NA.77

Properties

• Quality Level: 200
• Assay: ≥97% (HPLC)
• UniProt accession no.: O08725; P01189
• storage temp.: −20°C
• SMILES string: C[C@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc3cnc[nH]3)C(=O)N[C@@H](Cc4c[nH]c5ccccc45)C(=O)N[C@H](Cc6ccccc6)C(=O)N[C@@H](CCCCN)C(N)=O
• InChI: 1S/C46H56N12O6/c1-27(54-44(62)39(20-29-23-51-35-15-7-5-13-32(29)35)57-43(61)34(48)22-31-25-50-26-53-31)42(60)56-40(21-30-24-52-36-16-8-6-14-33(30)36)46(64)58-38(19-28-11-3-2-4-12-28)45(63)55-37(41(49)59)17-9-10-18-47/h2-8,11-16,23-27,34,37-40,51-52H,9-10,17-22,47-48H2,1H3,(H2,49,59)(H,50,53)(H,54,62)(H,55,63)(H,56,60)(H,57,61)(H,58,64)/t27-,34-,37-,38+,39+,40-/m0/s1
• InChI key: WZHKXNSOCOQYQX-FUAFALNISA-N
• Gene Information: human ... POMC(5443) ; rat ... Ghsr(84022)

Description

Amino Acid Sequence

His-Trp-Ala-Trp-Phe-Lys-NH2

Biochem/physiol Actions

Selective inhibitor of α-MSH activity in frog skin bioassay; identical to (His¹,Lys⁸)-GH which selectively releases growth hormone in vitro and in vivo; somatostatin antagonist.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves