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Fludrocortisone acetate

Name: Fludrocortisone acetate
Brand: SIGMA

synthetic, ≥98%, glucocorticoid activity, powder

Synonym(s):

9α-Fluoro-11β,17α,21-trihydroxy-4-pregnene-3,20-dione acetate, 9-Fluorocortisol acetate, 9-Fluorohydrocortisone acetate

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About This Item

Empirical Formula (Hill Notation):

C₂₃H₃₁FO₆

CAS Number:

514-36-3

Molecular Weight:

422.49

NACRES:

NA.77

PubChem Substance ID:

24894899

UNSPSC Code:

12352200

EC Number:

208-180-4

MDL number:

MFCD00864160

Assay:

≥98%

Form:

powder

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Properties

Product Name

Fludrocortisone acetate, ≥98%

biological source

synthetic

Quality Segment

100

sterility

non-sterile

assay

≥98%

form

powder

solubility

acetone: 50 mg/mL, clear, colorless to light yellow

shipped in

ambient

storage temp.

room temp

SMILES string

CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C

InChI

1S/C23H31FO6/c1-13(25)30-12-19(28)22(29)9-7-16-17-5-4-14-10-15(26)6-8-20(14,2)23(17,24)18(27)11-21(16,22)3/h10,16-18,27,29H,4-9,11-12H2,1-3H3/t16-,17-,18-,20-,21-,22-,23-/m0/s1

InChI key

SYWHXTATXSMDSB-GSLJADNHSA-N

Gene Information

human ... NR3C2(4306)

Description

General description

Fludrocortisone acetate is secreted by adrenal cortex. It increases the reabsorption of sodium and secretion of potassium and hydrogen. Fludrocortisone is used to treat cerebral salt wasting syndrome and adrenal insufficiency. Fludrocortisone improves the sensitivity of blood vessels to catecholamines and increases the blood volume.

Biochem/physiol Actions

Fludrocortisone acetate is a synthetic corticosteroid with more mineralocorticoid than glucocorticoid activity.

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This Item	BP159	1273003	Y0002475
Sigma-Aldrich F6127 Fludrocortisone acetate	BP159 Fludrocortisone acetate	USP 1273003 Fludrocortisone acetate	Y0002475 Fludrocortisone acetate for peak identification CRS
description ≥98%	description British Pharmacopoeia (BP) Reference Standard	description United States Pharmacopeia (USP) Reference Standard	description European Pharmacopoeia (EP) Reference Standard
form powder	form solid	form -	form -
assay ≥98%	assay -	assay -	assay -
Quality Level 100	Quality Level -	Quality Level -	Quality Level -
storage temp. room temp	storage temp. 2-8°C	storage temp. -	storage temp. 2-8°C
solubility acetone: 50 mg/mL, clear, colorless to light yellow	solubility -	solubility -	solubility -
shipped in ambient	shipped in -	shipped in -	shipped in -

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Pictograms

GHS08,GHS07

Signal Word

Warning

Hazard Codes

H302,H361

Precautionary Statements

P201 - P301 + P312 + P330 - P308 + P313

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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