E5406

Ethopropazine hydrochloride

≥98% (HPLC), butyrylcholinesterase inhibitor, powder

• Synonym(s): 10-(2-Diethylaminopropyl)phenothiazine, 10-[2-(Diethylamino)propyl]phenothiazine hydrochloride, Dibutil hydrochloride, Parkin
• Empirical Formula (Hill Notation): C₁₉H₂₄N₂S · HCl
• CAS Number: 1094-08-2
• Molecular Weight: 348.93
• NACRES: NA.77
• PubChem Substance ID: 329799070
• UNSPSC Code: 12352200
• EC Number: 214-134-4
• MDL number: MFCD00012653
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Properties

• Product Name: Ethopropazine hydrochloride, ≥98% (HPLC), powder
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white
• solubility: DMSO: >5 mg/mL at ~60 °C, clear
• storage temp.: 2-8°C
• SMILES string: Cl[H].CCN(CC)C(C)CN1c2ccccc2Sc3ccccc13
• InChI: 1S/C19H24N2S.ClH/c1-4-20(5-2)15(3)14-21-16-10-6-8-12-18(16)22-19-13-9-7-11-17(19)21;/h6-13,15H,4-5,14H2,1-3H3;1H
• InChI key: VXPCQISYVPFYRK-UHFFFAOYSA-N
• Gene Information: human ... CHRM1(1128)

Description

General description

Ethopropazine hydrochloride possess anticholinergic, antihistamine and antiadrenergic properties.

Biochem/physiol Actions

Ethoproprazine hydrochloride is an inhibitor of butyrylcholinesterase; antiparkinsonian

Ethoproprazine hydrochloride is an inhibitor of butyrylcholinesterase; antiparkinsonian. It reduces extrapyramidal motor effects, characteristic of Parkinson′s disease; also alleviates thermal hyperalgesia in rats.

Features and Benefits

This compound is featured on the Acetylcholine Synthesis and Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves