C5608
Collagen from rabbit skin
Bornstein and Traub Type I, powder
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About This Item
Form:
powder
Biological source:
rabbit skin
Pricing and availability is not currently available.
biological source
rabbit skin
Quality Segment
description
acid soluble
form
powder
technique(s)
cell culture | stem cell: suitable
solubility
aqueous acid: ≤10 mg/mL, aqueous sodium acetate buffer: soluble (0.01-0.5M)
UniProt accession no.
storage temp.
2-8°C
Gene Information
rabbit ... COL1A2(100008997)
General description
Collagen is classified into a number of structurally and genetically distinct types. We use the nomenclature proposed by Bornstein and Traub. Do not confuse Sigma type designations with recognized collagen classification types.
Application
Collagen-type 1 may be used in research of Idiopathic pulmonary fibrosis (IPF). Robust expression of collagen-type 1 is one distinctive feature of IPF. Additionally, collagen-type 1 has been used in studies on the effect of endoplasmic reticulum (ER) stress from IPF on myofibroblastic differentiation of lung fibroblasts. Collage-type 1 soluble in acidic solution produces three dimensional scaffolding useful in bioengineering and cell culture applications where biomaterials are needed to replace native collagen extracellular matrices.
Collagen Type I has been used as a scaffold for the growth in vitro of stem cells in a wide variety of biomaterial engineering studies.
Collagen Type I has been used as a scaffold for the growth in vitro of stem cells in a wide variety of biomaterial engineering studies.
Preparation Note
Prepared with modification of Gallop, P.M.
1 of 1
This Item | |||
|---|---|---|---|
| biological source rabbit skin | biological source rat tail | biological source bovine cartilage (tracheal) | biological source human |
| technique(s) cell culture | stem cell: suitable | technique(s) cell culture | mammalian: suitable | technique(s) - | technique(s) cell culture | stem cell: suitable |
| form powder | form powder | form powder | form powder |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility aqueous acid: ≤10 mg/mL, aqueous sodium acetate buffer: soluble (0.01-0.5M) | solubility soluble | solubility aqueous acid: soluble | solubility aqueous acid: ≤5 mg/mL |
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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