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Betaxolol hydrochloride

Name: Betaxolol hydrochloride
Brand: SIGMA

>98% (HPLC), calcium channel blocker, solid

Synonym(s):

SL 75212

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About This Item

Empirical Formula (Hill Notation):

C₁₈H₂₉NO₃ · HCl

CAS Number:

63659-19-8

Molecular Weight:

343.89

NACRES:

NA.77

PubChem Substance ID:

24278274

UNSPSC Code:

12352200

EC Number:

264-384-3

MDL number:

MFCD00242959

Assay:

>98% (HPLC)

Form:

solid

Storage condition:

desiccated

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Properties

Product Name

Betaxolol hydrochloride, >98% (HPLC)

Quality Segment

100

assay

>98% (HPLC)

form

solid

storage condition

desiccated

color

white

solubility

H₂O: soluble 36 mg/mL

originator

Alcon

SMILES string

Cl[H].CC(C)NCC(O)COc1ccc(CCOCC2CC2)cc1

InChI

1S/C18H29NO3.ClH/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16;/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3;1H

InChI key

CHDPSNLJFOQTRK-UHFFFAOYSA-N

Gene Information

human ... ADRB1(153)

Description

Application

Betaxolol hydrochloride has been used as a β1 blocking agent:

for the preparation of crystals of (R,S)-betaxolol (BE-IV).
to treat mammalian cells prior cell stimulation experiments.
to study the solid structure of metoprolol.

Biochem/physiol Actions

Betaxolol hydrochloride has the ability to block calcium channels. Betaxolol is a selective β1 adrenoreceptor antagonist. It has neuroprotective effects on retinal neurons.

Features and Benefits

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Alcon. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Show Differences

1 of 1

This Item	F1678	D8190	A9227
Sigma-Aldrich B5683 Betaxolol hydrochloride	Sigma-Aldrich F1678 R-(−)-Fluoxetine hydrochloride	Sigma-Aldrich D8190 3′,4′-Dichlorobenzamil hydrochloride	Sigma-Aldrich A9227 ABT-491 hydrochloride
assay >98% (HPLC)	assay >98% (HPLC)	assay >98% (HPLC)	assay ≥98% (HPLC)
form solid	form solid	form solid	form solid
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
storage condition desiccated	storage condition desiccated	storage condition -	storage condition desiccated
solubility H₂O: soluble 36 mg/mL	solubility H₂O: soluble >10 mg/mL	solubility DMSO: soluble 30 mg/mL, H₂O: insoluble	solubility H₂O: freely soluble 22 mg/mL
originator Alcon	originator Eli Lilly	originator -	originator Abbott

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pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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