89179

L-Threonine

≥99.5% (NT), BioXtra

• Synonym(s): (2S,3R)-2-Amino-3-hydroxybutyric acid
• Linear Formula: CH₃CH(OH)CH(NH₂)CO₂H
• CAS Number: 72-19-5
• Molecular Weight: 119.12
• Beilstein: 1721646
• EC Number: 200-774-1
• MDL number: MFCD00064270
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 57653332
• NACRES: NA.26

Properties

• product name: L-Threonine, BioXtra, ≥99.5% (NT)
• product line: BioXtra
• Assay: ≥99.5% (NT)
• form: powder or crystals
• optical activity: [α]20/D −28.5±0.5°, c = 5% in H₂O
• impurities: ≤0.5% foreign amino acids
• ign. residue: ≤0.1%
• loss: ≤0.1% loss on drying, 20 °C (HV)
• color: white to off-white
• mp: 256 °C (dec.) (lit.)
• solubility: H₂O: 50 mg/mL, clear, colorless
• anion traces: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤100 mg/kg
• cation traces: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; NH₄⁺: ≤500 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• SMILES string: C[C@@H](O)[C@H](N)C(O)=O
• InChI: 1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1
• InChI key: AYFVYJQAPQTCCC-GBXIJSLDSA-N

Description

Application

• Reconstruction the feedback regulation of amino acid metabolism to develop a non-auxotrophic L-threonine producing Corynebacterium glutamicum.: This research utilizes L-Threonine as an internal standard for the detection and optimize the production of L-Threonine on genetically modifying Corynebacterium glutamicum aiming at more sustainable and cost-effective bio-manufacturing processes (Liu et al., 2024).


• Threonine dehydrogenase regulates neutrophil homeostasis but not H3K4me3 levels in zebrafish.: This research utilises L-Threonine as a chemical treatment to study the enzymatic activity of threonine dehydrogenase in regulating neutrophil function in zebrafish (Li et al., 2024).

Other Notes

Preparation of threonine-sepharose, assay and purification of protein kinase C; Amino acid spacing in isotachophoresis on polyacrylamide gel - a critical evaluation; Growth requirement of various microorganisms.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves