53370

L-Histidine monohydrochloride monohydrate

≥99.0% (AT)

• Synonym(s): L-α-Amino-β-(4-imidazolyl)propionic acid monohydrochloride
• Empirical Formula (Hill Notation): C₆H₉N₃O₂ · HCl · H₂O
• CAS Number: 5934-29-2
• Molecular Weight: 209.63
• UNSPSC Code: 12352209
• NACRES: NA.77
• PubChem Substance ID: 329757872
• MDL number: MFCD00151027
• Beilstein/REAXYS Number: 4168261
• eCl@ss: 32160406
• Assay: ≥99.0% (AT)
• Form: solid

Properties

• Quality Segment: 100
• assay: ≥99.0% (AT)
• form: solid
• optical activity: [α]20/D +9.5±0.5°, c = 5% in 5 M HCl
• impurities: ≤0.3% foreign amino acids
• mp: 254 °C (dec.) (lit.)
• solubility: H₂O: 1 g/10 mL, clear, colorless (hot)
• anion traces: sulfate (SO₄^2-): ≤100 mg/kg
• cation traces: Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, NH₄⁺: ≤500 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg
• SMILES string: O.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O
• InChI: 1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1
• InChI key: CMXXUDSWGMGYLZ-XRIGFGBMSA-N

Description

General description

L-Histidine is a hydrophilic essential amino acid that has a basic sidechain containing an imidazole group.

Biochem/physiol Actions

L-Histidine is biosynthesized from ATP, 5-phosphoribosyl-1-pyrophosphate (PRPP), and glutamine. This essential amino acid can be degraded to glutamate by histidiase, urocanase and imidazolonepropionase; it is also the precursor of histamine by action of histidine decarboxylase.

Safety Information

• Storage Class: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)