51454

Methicillin sodium salt

≥95% (HPLC)

• Synonym(s): Sodium (2,6-dimethoxyphenyl)penicillin, Sodium methicillin
• Empirical Formula (Hill Notation): C₁₇H₁₉N₂NaO₆S
• CAS Number: 132-92-3
• Molecular Weight: 402.40
• NACRES: NA.85
• PubChem Substance ID: 329757690
• UNSPSC Code: 51283503
• EC Number: 205-083-9
• MDL number: MFCD07787409

Properties

• biological source: synthetic
• Quality Segment: 200
• assay: ≥95% (HPLC)
• form: powder
• color: white to off-white
• antibiotic activity spectrum: Gram-positive bacteria
• mode of action: cell wall synthesis | interferes
• storage temp.: 2-8°C
• SMILES string: [Na+].COc1cccc(OC)c1C(=O)N[C@H]2C3SC(C)(C)[C@@H](N3C2=O)C([O-])=O
• InChI: 1S/C17H20N2O6S.Na/c1-17(2)12(16(22)23)19-14(21)11(15(19)26-17)18-13(20)10-8(24-3)6-5-7-9(10)25-4;/h5-7,11-12,15H,1-4H3,(H,18,20)(H,22,23);/q;+1/p-1/t11-,12+,15-;/m1./s1
• InChI key: MGFZNWDWOKASQZ-UMLIZJHQSA-M

Description

Application

Methicillin is used to study bacterium susceptibility , methicillin-resistance in Staphylococcus aureus [1], and to inhibit cell-wall synthesis [2].

Biochem/physiol Actions

Methicillin inhibits cell wall synthesis. In Legionella pneumophila, methicillin causes the formation of membranous lesions through which cytoplasmic contents are lost [2].

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Light sensitive

Safety Information

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H315,H317,H319,H334,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves