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P2256

Sigma-Aldrich

Sodium pyruvate

ReagentPlus®, ≥99%

Synonym(s):

α-Ketopropionic acid sodium salt, 2-Oxopropanoic acid sodium salt, Pyruvic acid sodium salt

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About This Item

Linear Formula:
CH3COCOONa
CAS Number:
113-24-6
Molecular Weight:
110.04
Beilstein:
3568341
EC Number:
204-024-4
MDL number:
MFCD00002586
UNSPSC Code:
12352100
PubChem Substance ID:
24898303
NACRES:
NA.21

Quality Level

200

product line

ReagentPlus®

Assay

≥99%

form

powder

loss

≤0.5% loss on drying

mp

>300 °C (lit.)

solubility

H2O: 100 mg/mL, clear, colorless to faintly yellow

cation traces

heavy metals (as Pb): ≤20 ppm

storage temp.

2-8°C

SMILES string

[Na+].CC(=O)C([O-])=O

InChI

1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1

InChI key

DAEPDZWVDSPTHF-UHFFFAOYSA-M

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General description

Sodium pyruvate (SP) is a simplest keto-acid. It crystallizes as very thin plates and belongs to the monoclinic system. Its utility in Knoevenagel condensation carried out in an aqueous medium has been examined. The standard molar enthalpy of formation and molar enthalpy of dissolution of SP at infinite dilution have been obtained. Its efficacy in treating mitochondrial DNA depletion syndromes has been investigated.

Application

Sodium pyruvate has been used:
  • To prepare Bull Tyrode′s albumin-lactate-pyruvate diluent.
  • In pyruvate tolerance test.
  • To prepare oligodendrocyte culture medium.

Other Notes

Go to Redi-Dri™ Product Listing 792500

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317,H319

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1B

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000394678
0000394662
0000391659
0000387751
0000386349

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The crystal structure of sodium pyruvate.
Tavale SS, et al.
Acta Crystallographica, 14(12), 1281-1286 (1961)
Pyruvate therapy for mitochondrial DNA depletion syndrome.
Saito K, et al.
Biochim. Biophys. Acta Gen. Subj., 1820(5), 632-636 (2012)
"On Water": Rapid Knoevenagel Condensation Using Sodium Pyruvate.
Heravi MM, et al.
Letters in Organic Chemistry, 3(4), 297-299 (2006)
Crystal structure and thermochemical properties of a novel coordination compound sodium pyruvate C3H3O3Na(s).
Gao ZF, et al.
The Journal of Chemical Thermodynamics, 78, 189-196 (2014)
Donald A Morgan et al.
Diabetes, 64(6), 1976-1987 (2015-01-22)
Melanocortin 4 receptor (MC4R) signaling mediates diverse physiological functions, including energy balance, glucose homeostasis, and autonomic activity. Although the lateral hypothalamic area (LHA) is known to express MC4Rs and to receive input from leptin-responsive arcuate proopiomelanocortin neurons, the physiological functions
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