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97336

D-Sorbitol

Name: <SC>D</SC>-Sorbitol
Brand: SIAL

liquid, tested according to Ph. Eur.

Synonym(s):

Sorbitolum liquidum non cristallisabile, D-Glucitol

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About This Item

Empirical Formula (Hill Notation):

C₆H₁₄O₆

CAS Number:

50-70-4

Molecular Weight:

182.17

UNSPSC Code:

12352201

NACRES:

NA.21

PubChem Substance ID:

329770356

EC Number:

200-061-5

Beilstein/REAXYS Number:

1721899

MDL number:

MFCD00004708

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Properties

Quality Level

100

agency

tested according to Ph. Eur.

vapor density

<1 (vs air)

vapor pressure

<0.1 mmHg ( 25 °C)

assay

72-92%

form

liquid

impurities

28-32% water

color

white

useful pH range

5.0-7 (25 °C, 182 g/L)

mp

98-100 °C (lit.)

solubility

water: soluble 182 g/L at 20 °C (68 °F)

application(s)

advanced drug delivery

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1

InChI key

FBPFZTCFMRRESA-JGWLITMVSA-N

Description

Other Notes

To gain a comprehensive understanding of our extensive range of Sugar alcohols for your research, we encourage you to visit our Carbohydrates Category page.

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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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FUS/TLS assembles into stress granules and is a prosurvival factor during hyperosmolar stress.

Reddy Ranjith K Sama et al.

Journal of cellular physiology, 228(11), 2222-2231 (2013-04-30)

FUsed in Sarcoma/Translocated in LipoSarcoma (FUS/TLS or FUS) has been linked to several biological processes involving DNA and RNA processing, and has been associated with multiple diseases, including myxoid liposarcoma and amyotrophic lateral sclerosis (ALS). ALS-associated mutations cause FUS to

Assessment of the hepatic circulation in humans: new concepts based on evidence derived from a D-sorbitol clearance method.

G Molino et al.

The Journal of laboratory and clinical medicine, 131(5), 393-405 (1998-05-30)

D-Sorbitol (SOR) is safe, is easy to measure, and has an exceptionally high extraction ratio in the normal liver of 0.93+/-0.05 (mean+/-SD). Together with the general interest in hepatic hemodynamics, these facts motivated us to review the usefulness of this

An exploratory randomised double-blind and placebo-controlled phase 2 study of a combination of baclofen, naltrexone and sorbitol (PXT3003) in patients with Charcot-Marie-Tooth disease type 1A.

Shahram Attarian et al.

Orphanet journal of rare diseases, 9, 199-199 (2014-12-19)

Charcot-Marie-Tooth type 1A disease (CMT1A) is a rare orphan inherited neuropathy caused by an autosomal dominant duplication of a gene encoding for the structural myelin protein PMP22, which induces abnormal Schwann cell differentiation and dysmyelination, eventually leading to axonal suffering

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Global Trade Item Number

SKU	GTIN
97336-1KG-F	04061838170330