67028

Methylglyoxal solution

technical, ~40% in H₂O

• Synonym(s): Acetylformaldehyde, Pyruvaldehyde, Pyruvic aldehyde
• Linear Formula: CH₃COCHO
• CAS Number: 78-98-8
• Molecular Weight: 72.06
• UNSPSC Code: 12352100
• NACRES: NA.22
• PubChem Substance ID: 329760261
• MDL number: MFCD00006960
• Beilstein/REAXYS Number: 906750

Properties

• grade: technical
• Quality Segment: 200
• concentration: ~40% in H₂O
• density: 1.19 g/mL at 20 °C
• functional group: aldehyde, ketone
• storage temp.: 2-8°C
• SMILES string: [H]C(=O)C(C)=O
• InChI: 1S/C3H4O2/c1-3(5)2-4/h2H,1H3
• InChI key: AIJULSRZWUXGPQ-UHFFFAOYSA-N

Description

General description

Methylglyoxal is a toxic endogenous by-product of glycolysis. It is a reactive dicarbonyl compound that promotes non-enzymatic glycation of proteins to yield irreversible advanced glycated end products, leading to the cross-linking or degradation of proteins.

Application

Methylglyoxal solution is used in cytotoxic studies.

Safety Information

• pictograms: GHS08,GHS05,GHS07
• signalword: Danger
• hcodes: H290,H317,H318,H341
• pcodes: P202 - P234 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Eye Dam. 1 - Met. Corr. 1 - Muta. 2 - Skin Sens. 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
• Storage Class: 10 - Combustible liquids