MABD24A4

Anti-NANOG Antibody, clone 7F7.1, Alexa Fluor^™ 488 conjugate

clone 7F7.1, from mouse, ALEXA FLUOR^™ 488

• Synonym(s): Homeobox protein NANOG, Homeobox transcription factor Nanog, hNanog
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: ALEXA FLUOR^™ 488
• Clone: 7F7.1, monoclonal
• Application: ICC
• Citations: 8

Properties

• biological source: mouse
• Quality Segment: 100
• conjugate: ALEXA FLUOR^™ 488
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 7F7.1, monoclonal
• species reactivity: human
• technique(s): immunocytochemistry: suitable
• isotype: IgG2a
• NCBI accession no.: NP_079141
• UniProt accession no.: Q9H9S0
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... NANOG(79923)

Description

General description

NANOG (Homeobox protein NANOG) is a member of the Nanog homeobox family of DNA-binding proteins. It is expressed in embryonic stem cells and confers pluripotency on these cells. Once embryonic stem cells become differentiated, NANOG expression is suppressed. NANOG is involved in the Hedgehog/Gli1 signaling pathway which has been implicated in the development and growth of various types of tumors. NANOG has also been identified as a key transcription factor used to generate induced pluripotent stem cells.

The uncojugated parent antibody (Catalog No. MABD24) has an observed MW of 39 kDa

Application

Anti-NANOG Antibody, clone 7F7.1, Alexa Fluor 488 conjugate.

Physical form

Purified mouse monoclonal IgG2a conjugated to Alexa Fluor^™ 488 in PBS with 0.1% sodium azide and 15mg/ml BSA.

Analysis Note

Evaluated by Immunocytochemistry in H9 human embryonic stem cells. Immunocytochemsitry Analysis: A 1:100 dilution of this antibody detected NANOG in H9 human embryonic stem cells.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

ALEXA FLUOR is a trademark of Life Technologies

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• WGK: WGK 2