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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
ALEXA FLUOR™ 488
Clone:
mGalC, monoclonal
Application:
ICC
Citations:
3
biological source
mouse
Quality Segment
conjugate
ALEXA FLUOR™ 488
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
mGalC, monoclonal
species reactivity
rabbit, rat
species reactivity (predicted by homology)
human, bovine (immunogen homology), chicken, mouse
technique(s)
immunocytochemistry: suitable
isotype
IgG3
shipped in
wet ice
target post-translational modification
unmodified
General description
Galactocerebroside (GalC) is a major galactosphingolipid of myelin which plays a role in myelination. GalC is a very useful, specific marker for oligodendroglial lineage.
Application
Detect Galactocerebroside using this Anti-Galactocerebroside Antibody, clone mGalC, Alexa Fluor™488 Conjugate validated for use in ICC.
Biochem/physiol Actions
This antibody recognizes Galactocerebroside (GalC), sulfatide, psychosine and other galactolipids. Cross-reacts with the sulfatide ester of GalC, but to a 16-fold to a lesser extent. No cross-reactivity with sphingosine, ceramide, mixed ganglioside or glucocerebroside. Binds specifically with oligodendrocytes and Schwann cells.
Physical form
Purified mouse monoclonal IgG3 conjugated to Alexa Fluor™ 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Analysis Note
Control
Rat oligodendrocyte cells
Rat oligodendrocyte cells
Evaluated by Immunocytochemistry in rat oligodendrocyte cells.
Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Galactocerebroside in rat oligodendrocyte cells. Performed without Triton.
Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Galactocerebroside in rat oligodendrocyte cells. Performed without Triton.
Legal Information
ALEXA FLUOR is a trademark of Life Technologies
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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