IM1014
Anti-Matriptase/MT-SP1 Rabbit pAb
liquid, Calbiochem®
Synonym(s):
Anti-Membrane-Type Serine Protease 1, Anti-Suppressor of Tumorgenicity 14
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
liquid
contains
≤0.1% sodium azide as preservative
species reactivity
human
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
isotype
IgG
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Gene Information
human ... ST14(6768)
General description
Immunoaffinity purified rabbit polyclonal antibody. Recognizes the ~75 kDa matriptase protein.
Recognizes the ~75 kDa matriptase protein in MCF-7 cells.
This Anti-Matriptase/MT-SP1 Rabbit pAb is validated for use in Immunoblotting, Immunoprecipitation for the detection of Matriptase/MT-SP1.
Immunogen
Human
a synthetic peptide corresponding to amino acids near the C-terminus of human matriptase
Application
Immunoblotting (1:500-1:2000)
Immunoprecipitation (5-20 g/mg lysate)
Packaging
Please refer to vial label for lot-specific concentration.
Warning
Toxicity: Highly Toxic (H)
Physical form
In Tris-citrate/phosphate buffer, pH 7.0-8.0.
Reconstitution
Following initial use, aliquot and freeze (-20°C) for long-term storage. Avoid freeze/thaw cycles.
Analysis Note
Positive Control
MCF-7 cells
MCF-7 cells
Other Notes
Antibody should be titrated for optimal results in individual systems.
Santin, A.D., et al. 2003. Cancer98, 1898.
Takeuchi, T., et al. 2000. J. Biol. Chem.275, 26333.
Lin, C.Y., et al. 1999. J. Biol. Chem.274, 18231.
Takeuchi, T., et al. 1999. Proc. Natl. Acad. Sci. USA96, 11054.
Takeuchi, T., et al. 2000. J. Biol. Chem.275, 26333.
Lin, C.Y., et al. 1999. J. Biol. Chem.274, 18231.
Takeuchi, T., et al. 1999. Proc. Natl. Acad. Sci. USA96, 11054.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Not finding the right product?
Try our Product Selector Tool.
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Sine Godiksen et al.
PloS one, 8(10), e77146-e77146 (2013-11-10)
Matriptase is a member of the family of type II transmembrane serine proteases that is essential for development and maintenance of several epithelial tissues. Matriptase is synthesized as a single-chain zymogen precursor that is processed into a two-chain disulfide-linked form
Sine Godiksen et al.
The Biochemical journal, 413(2), 251-259 (2008-04-12)
HAI-1 [HGF (hepatocyte growth factor) activator inhibitor-1] is a Kunitz-type transmembrane serine protease inhibitor that forms inhibitor complexes with the trypsin-like serine protease, matriptase. HAI-1 is essential for mouse placental development and embryo survival and together with matriptase it is
Ke-Hung Tsui et al.
Journal of molecular endocrinology, 49(2), 153-163 (2012-08-09)
Growth differentiation factor-15 (GDF15), a member of the transforming growth factor-β superfamily, is associated with human cancer progress. We evaluated the role GDF15 plays in tumorigenesis of prostate carcinoma PC-3 cells. Results from real-time RT-PCR and ELISA revealed that expression
Jennifer M Milner et al.
Arthritis and rheumatism, 62(7), 1955-1966 (2010-05-28)
Increasing evidence implicates serine proteinases in pathologic tissue turnover. The aim of this study was to assess the role of the transmembrane serine proteinase matriptase in cartilage destruction in osteoarthritis (OA). Serine proteinase gene expression in femoral head cartilage obtained
Ki Yeon Kim et al.
Journal of experimental & clinical cancer research : CR, 38(1), 363-363 (2019-08-21)
In order to develop a new immunotherapeutic agent targeting metastatic breast cancers, we chose to utilize autocatalytic feature of the membrane serine protease Prss14/ST14, a specific prognosis marker for ER negative breast cancer as a target molecule. The study was
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service