GF176
TGF-β-III Protein, Human Recombinant
TGF-β-III (transforming growth factor beta III) is one of three closely related mammalian members of the large TGF-β superfamily.
Synonym(s):
Transforming Growth Factor Beta 3, TGF-Beta-3, TGF-Beta-III
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About This Item
UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.77
Recommended Products
Quality Level
Assay
>98% (SDS-PAGE and HPLC)
impurities
<0.1 μg/mg protein endotoxin (<1 EU/μg)
UniProt accession no.
shipped in
dry ice
Gene Information
human ... TGFB3(7043)
General description
Product Source: E. coli.
TGF-β-III (transforming growth factor beta III) is one of three closely related mammalian members of the large TGF-β superfamily. TGF-β-I, TGF-β-II and TGF-β-III are highly pleiotropic cytokines that are proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial mesenchymal transition. TGF-β3 regulates molecules involved in cellular adhesion and extracellular matrix formation during the process of palate development. TGF-β3 also plays an essential role in controlling the development of lungs in mammals and controls wound healing by regulating the movements of epidermal and dermal cells in injured skin. Recombinant TGF-β-III is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.
Application
Research Category
Stem Cell Research
Stem Cell Research
Research Sub Category
Growth Factors & Receptors
Growth Factors & Receptors
Quality
Determined by TGF-β-III’s ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells. The expected ED50 is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.
Physical form
Product is filtered through a 0.2 micron filter before lyophilization.
Storage and Stability
Store at -20°C for up to 6 months from date of receipt.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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