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MilliporeSigma

8.55130

Rink Amide AM resin (100-200 mesh)

Novabiochem®

Synonym(s):

Rink Amide AM resin (100-200 mesh), 4-(2′,4′-Dimethoxyphenyl-Fmoc-aminomethyl)-phenoxyacetamido-aminomethyl resin

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About This Item

CAS Number:
MDL number:
NACRES:
NA.22
UNSPSC Code:
12352111
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Quality Level

product line

Novabiochem®

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

amine

storage temp.

2-30°C

General description

This support comprises the modified Rink amide linker attached to aminomethylpolystyrene and is an ideal tool for the Fmoc SPPS of peptide amides. Cleavage from this resin can be effected by a single step treatment with 95% TFA, providing peptide amides in high yields and purities.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Application

Applications of Rink Amide AM resin (100-200 mesh)in solid phase organic synthesis include:
  • In the synthesis of quinazolinone derivatives via intramolecular transamidation.
  • In the preparation of 2-aminoquinazoline-based compounds using solid-phase peptide synthesis (SPPS) methodology.
  • For the synthesis of α-aryl ketones via a palladium-catalyzed coupling reaction.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
855130000504027269177003
855130010004027269238773
855130025004027269238780
855130000104027269176990
855130100004027269843397
855130002504027269177010

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