539515

Prothrombin, Human Plasma

• Synonym(s): Prothrombin, Human Plasma, Coagulation Factor II
• CAS Number: 9001-26-7
• UNSPSC Code: 12352202
• NACRES: NA.25

Properties

• Assay: >95% (SDS-PAGE)
• Quality Level: 200
• form: lyophilized
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• solubility: water: soluble
• shipped in: ambient
• storage temp.: 2-8°C

Description

General description

Native prothrombin from human plasma. Vitamin K-dependent glycoprotein synthesized in the liver. Conversion to thrombin is a key step in the blood coagulation pathway and catalyzes the coagulation of fibrinogen. Clinically, cases of selective deficiency are rare, although in cases of liver cirrhosis, prothrombin is decreased.

Native prothrombin from human plasma. Vitamin K-dependent glycoprotein synthesized in the liver. Conversion to thrombin is a key step in the blood coagulation pathway and catalyzes the coagulation of fibrinogen. Clinically, cases of selective deficiency are rare, although, in cases of liver cirrhosis, prothrombin is decreased.

Warning

Toxicity: Standard Handling (A)

Physical form

Lyophilized from 100 mM NaCl, 20 mM Tris-HCl, pH 7.4.

Preparation Note

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C.

Please refer to the label for lot-specific reconstitution volume.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3