05-1066
Anti-Insulin Antibody, clone E11D7
clone E11D7, from mouse
Synonym(s):
Anti-IDDM, Anti-IDDM1, Anti-IDDM2, Anti-ILPR, Anti-IRDN, Anti-MODY10, Anti-PNDM4
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All Photos(2)
About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
mouse
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
E11D7, monoclonal
species reactivity
human
species reactivity (predicted by homology)
rat, mouse
packaging
antibody small pack of 25 μg
technique(s)
ELISA: suitable
immunohistochemistry: suitable (paraffin)
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
ambient
target post-translational modification
unmodified
Gene Information
human ... INS(3630)
mouse ... Ins1(16333)
rat ... Ins1(24505)
General description
Insulin is a polypeptide hormone that regulates carbohydrate metabolism. Apart from being the primary agent in carbohydrate homeostasis, it has effects on fat metabolism.
Specificity
Recognizes insulin
Immunogen
Epitope: Insulin
Human recombinant Insulin
Application
Anti-Insulin Antibody, clone E11D7 detects level of Insulin & has been published & validated for use in ELISA, IH(P).
ELISA (Direct) Analysis:
Insulin-coated plate was incubated with Anti-Insulin, clone E11D7 in 2-fold serial dilutions diluted in PBST from 5 μg/mL to 0.01 μg/mL.
Insulin-coated plate was incubated with Anti-Insulin, clone E11D7 in 2-fold serial dilutions diluted in PBST from 5 μg/mL to 0.01 μg/mL.
Research Category
Signaling
Metabolism
Signaling
Metabolism
Research Sub Category
Insulin/Energy Signaling
Glucose/Glycogen Metabolism
Metabolic Hormones & Receptors
Insulin/Energy Signaling
Glucose/Glycogen Metabolism
Metabolic Hormones & Receptors
Quality
Immunohistochemistry Analysis:
20 μg/mL of this antibody detected insulin in β cells.
20 μg/mL of this antibody detected insulin in β cells.
Target description
6 kDa
Physical form
Format: Purified
Protein G Purified
Purified mouse monolconal IgG1κ in 0.1M Tris-Glycine (pH7.4), 150mM NaCl with 0.05%NaN3
Storage and Stability
Stable for 1 year at 2-8ºC from date of receipt.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Product No.
Description
Pricing
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Mi Ran Choi et al.
Journal of ginseng research, 41(4), 503-512 (2017-10-13)
Chronic heavy alcohol consumption may raise the risk of developing type 2 diabetes mellitus. Saponins inhibit apoptosis of pancreatic islet cells and reduce lipid parameters. The present study was designed to investigate the effect of saponin on chronic ethanol-treated diabetic
Yoshimitsu Taguchi et al.
The Journal of biological chemistry, 291(23), 12029-12038 (2016-04-10)
Sphingosine-1-phosphate (S1P) is a sphingolipid metabolite that regulates basic cell functions through metabolic and signaling pathways. Intracellular metabolism of S1P is controlled, in part, by two homologous S1P phosphatases (SPPases), 1 and 2, which are encoded by the Sgpp1 and
Activation of PPAR? up-regulates the expression of insulin gene transcription factor MafA and ameliorates glucose-induced insulin secretion impaired by palmitate.
Mingming Cao,Yang Long,Yuzhen Tong,Jun Wan,Nanwei Tong
Molecular and Cellular Biochemistry null
Gabriel Cao et al.
PloS one, 16(6), e0243340-e0243340 (2021-06-12)
The objective of this work was to analyze the structural changes of the pancreatic islets in rats, after 6 month consuming regular and light cola for 6 months. Also, we have analyzed the possible role of PDX-1 in that process.
Rehab F Abdel-Rahman et al.
Journal of nutritional science, 9, e2-e2 (2020-02-12)
Ficus deltoidea var. deltoidea Jack (FD) is a well-known plant used in Malay folklore medicine to lower blood glucose in diabetic patients. For further research of the antihyperglycemic mechanisms, the protein tyrosine phosphatase 1B (PTP1B)-inhibitory effect of FD was analysed
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