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227757

Sigma-Aldrich

Palladium

sulfided, extent of labeling: 5 wt. % loading (dry basis), matrix activated carbon, wet support, (wet)

Synonym(s):

Palladium on carbon, Pd/C

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About This Item

Linear Formula:
Pd
Molecular Weight:
106.42
MDL number:
MFCD03457879
UNSPSC Code:
12161600
PubChem Substance ID:
24853652
NACRES:
NA.22

form

(wet)

contains

≤50% water

reaction suitability

core: palladium
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst

extent of labeling

5 wt. % loading (dry basis)

weight

Unit weight excludes weight of water

matrix

activated carbon, wet support

SMILES string

[Pd]

InChI

1S/Pd

InChI key

KDLHZDBZIXYQEI-UHFFFAOYSA-N

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Application

Catalyst for:
  • Stille reaction
  • Hydrogenation reactions
  • Suzuki-Miyaura cross-coupling and Heck-Mizoroki reactions
  • Deoxygenation
  • Oxidation reactions
  • Coupling reactions

Pictograms

Flame
GHS02

Signal Word

Danger

Hazard Statements

H228

Hazard Classifications

Flam. Sol. 1

Storage Class Code

4.1B - Flammable solid hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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John R Hornick et al.
Journal of experimental & clinical cancer research : CR, 31, 41-41 (2012-05-04)
Sigma-2 receptor ligands have been studied for treatment of pancreatic cancer because they are preferentially internalized by proliferating cells and induce apoptosis. This mechanism of apoptosis is poorly understood, with varying reports of caspase-3 dependence. We evaluated multiple sigma-2 receptor
Carmen Abate et al.
ChemMedChem, 6(1), 73-80 (2010-11-12)
Many new chemotherapeutic agents are under preclinical investigation and, despite efforts to more selectively target cancer cells, limitations such as toxicity and inherent resistance are often encountered. Therefore, alternative strategies are needed to treat cancer and overcome such limitations. We
Carmen Abate et al.
Journal of medicinal chemistry, 57(8), 3314-3323 (2014-04-05)
Despite the promising potentials of σ2 receptors in cancer therapy and diagnosis, there are still ambiguities related to the nature and physiological role of the σ2 protein. With the aim of providing potent and reliable tools to be used in
Carmen Abate et al.
ChemMedChem, 7(10), 1847-1857 (2012-08-15)
σ(2) Receptor research is receiving increasing interest with regard to the potential of σ(2) proteins as targets for tumor therapy and diagnosis. Nevertheless, knowledge about the σ(2) receptor is far from conclusive. The paucity and modest affinity of known σ(2)
Mauro Niso et al.
ChemMedChem, 8(12), 2026-2035 (2013-10-10)
With the aim of contributing to the development of novel antitumor agents, high-affinity σ2 receptor agonists were developed, with 6,7-dimethoxy-2-[4-[1-(4-fluorophenyl)-1H-indol-3-yl]butyl]-1,2,3,4-tetrahydroisoquinoline (15) and 9-[4-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)butyl]-9H-carbazole (25) showing exceptional selectivity for the σ2 subtype. Most of the compounds displayed notable antiproliferative activity in
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