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1478301

USP

Olanzapine

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

2-Methyl-4-(4-methyl-1-piperazinyl)- 10H-thieno[2,3-b][1,5]benzodiazepine

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About This Item

Fórmula empírica (notación de Hill):
C17H20N4S
Número de CAS:
132539-06-1
Peso molecular:
312.43
Beilstein:
7655141
Número MDL:
MFCD00866702
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329750606
NACRES:
NA.24
En este momento no podemos mostrarle ni los precios ni la disponibilidad

grado

pharmaceutical primary standard

familia API

olanzapine

fabricante / nombre comercial

USP

aplicaciones

pharmaceutical (small molecule)

Formato

neat

cadena SMILES

CN1CCN(CC1)C2=Nc3ccccc3Nc4sc(C)cc24

InChI

1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3

Clave InChI

KVWDHTXUZHCGIO-UHFFFAOYSA-N

Información sobre el gen

human ... DRD2(1813) , DRD3(1814) , DRD4(1815) , HTR2A(3356) , HTR2C(3358)

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Olanzapine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Olanzapine and Fluoxetine Capsules
  • Olanzapine Orally Disintegrating Tablets
  • Olanzapine Tablets

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

Sales restrictions may apply.

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Olanzapine Related Compound C, United States Pharmacopeia (USP) Reference Standard

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PHR2537

Olanzapine Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

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Olanzapine Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2538

Olanzapine Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

Pictogramas

Skull and crossbones
GHS06

Palabra de señalización

Danger

Frases de peligro

H301,H315,H317,H336

Clasificaciones de peligro

Acute Tox. 3 Oral - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Órganos de actuación

Central nervous system

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

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Certificados de análisis (COA)

Lot/Batch Number

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Rajendra P Shukla et al.
Journal of neural transmission (Vienna, Austria : 1996), 127(2), 291-299 (2020-01-08)
Olanzapine is a thienobenzodiazepine compound. It is one of the newer types of antipsychotic drugs used in the treatment of schizophrenia and other psychotic disorders. Several methods have been reported for analyzing olanzapine in its pure form or combined with
Mauricio Tohen et al.
Archives of general psychiatry, 60(11), 1079-1088 (2003-11-12)
Despite the longer duration of the depressive phase in bipolar disorder and the frequent clinical use of antidepressants combined with antipsychotics or mood stabilizers, relatively few controlled studies have examined treatment strategies for bipolar depression. To examine the use of
Delia Bishara et al.
Journal of clinical psychopharmacology, 33(3), 329-335 (2013-04-24)
To conduct a systematic review examining the relationships between olanzapine dose, clinical outcome, dopamine occupancy, and plasma concentration; and to evaluate the potential for therapeutic drug monitoring. A search using Embase, Medline, and Pubmed was conducted; and the literature was
Elizabeth Brunner et al.
BMC pharmacology & toxicology, 14, 38-38 (2013-08-02)
Olanzapine use has been reported during pregnancy and breastfeeding, but there are no controlled clinical trials assessing the safety of olanzapine exposure to infants and fetuses. The purpose of this report was to review and analyze prospective post-marketing cases of
Christopher M Hocking et al.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 22(4), 1143-1151 (2014-02-14)
Newer drugs incorporated in prophylactic regimens for chemotherapy-induced nausea and vomiting (CINV) have resulted in significantly reduced rates of this feared complication of cytotoxic chemotherapy. However, both delayed chemotherapy-induced nausea and breakthrough CINV remain difficult areas of management and require
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