1367561

Linezolid

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: N-[(5S)-3-[3-fluoro-4-(4-morfolinil)fenil]-2-oxo-5-oxazolidinil]metil]acetamida, PNU-100766, U-100766
• Fórmula empírica (notación de Hill): C₁₆H₂₀FN₃O₄
• Número CAS: 165800-03-3
• Peso molecular: 337.35
• UNSPSC Code: 41116107
• NACRES: NA.24
• MDL number: MFCD00937825

Propiedades

• grade: pharmaceutical primary standard
• agency: USP
• API family: linezolid
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: CC(=O)NC[C@H]1CN(C(=O)O1)c2ccc(N3CCOCC3)c(F)c2
• InChI: 1S/C16H20FN3O4/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-23-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1
• InChI key: TYZROVQLWOKYKF-ZDUSSCGKSA-N

Descripción

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Linezolid USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Linezolid Tablets

Biochem/physiol Actions

Linezolid es una oxazolidinina antimicrobiana. Inhibe la traducción del ARNm bacteriano y es un inhibidor débil, reversible y no selectivo de la monoaminooxidasa.

Linezolid es una oxazolidinona antimicrobiana. Se une a un sitio del ARN ribosómico 23S bacteriano de la subunidad 50S y evita la formación de un complejo de iniciación 70S funcional, inhibiendo así la traducción del ARNm bacteriano. Linezolid es también un débil inhibidor no selectivo y reversible de la monoaminooxidasa.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Información de seguridad

• pictograms: GHS08
• signalword: Danger
• hcodes: H372
• pcodes: P260
• Hazard Classifications: STOT RE 1 Oral
• target_organs: Bone
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable