T0557

Taurodesoxicolato de sodio hydrate

BioXtra, ≥97% (TLC)

• Sinónimos: Ácido 2-([3α,12α-dihidroxi-24-oxo-5β-colan-24-il]amino)etanosulfónico, Ácido taurodesoxicólico sodium salt hydrate
• Fórmula lineal: C₂₆H₄₄NO₆SNa · xH₂O
• Número de CAS: 207737-97-1
• Peso molecular: 521.69 (anhydrous basis)
• Beilstein/REAXYS Number: 3901204
• MDL number: MFCD00149238
• UNSPSC Code: 12161900
• PubChem Substance ID: 24899897
• NACRES: NA.25

Propiedades

• description: anionic
• product line: BioXtra
• assay: ≥97% (TLC)
• mol wt: micellar avg mol wt 3100
• aggregation number: 6
• impurities: ≤0.002% Phosphorus (P); ≤0.1% Insoluble matter
• CMC: 1-4 mM (20-25°C)
• solubility: H₂O: 0.5 M, clear, colorless to faintly yellow
• anion traces: chloride (Cl^-): ≤0.5%; sulfate (SO₄^2-): ≤0.05%
• cation traces: Al: ≤0.0005%; Ca: ≤0.005%; Cu: ≤0.0005%; Fe: ≤0.0005%; K: ≤0.01%; Mg: ≤0.005%; NH₄⁺: ≤0.05%; Pb: ≤0.001%; Zn: ≤0.0005%
• SMILES string: O.[Na+].C[C@H](CCC(=O)NCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
• InChI: 1S/C26H45NO6S.Na.H2O/c1-16(4-9-24(30)27-12-13-34(31,32)33)20-7-8-21-19-6-5-17-14-18(28)10-11-25(17,2)22(19)15-23(29)26(20,21)3;;/h16-23,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);;1H2/q;+1;/p-1/t16-,17-,18-,19+,20-,21+,22+,23+,25+,26-;;/m1../s1
• InChI key: OLPIZAYYAVQETM-GGPRKOIFSA-M

Descripción

General description

Sodium tauroursodeoxycholate is a bile salt which is naturally present in the small bowel.

Application

Sodium tauroursodeoxycholate has been used in a study to assess short-term feedback regulation of bile salt uptake in rodent liver. It has also been used in a study to investigate its potential to resolve endoplasmic reticulum (ER) stress in intestinal epithelial cells. It is also used for isolation of membrane proteins including inner mitochondrial membrane proteins.

Detergente aniónico relacionado con las sales biliares utilizado para el aislamiento de las proteínas de membrana, entre ellas las proteínas de la membrana mitocondrial interna.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)