SRP8028

DR6 (human): FC (human)

recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)

• Sinónimos: CD358, TNFRSF21, Tumor necrosis factor receptor superfamily member 21
• Código UNSPSC: 12352202
• NACRES: NA.32

Propiedades

• origen biológico: human
• recombinante: expressed in HEK 293 cells
• Ensayo: >95% (SDS-PAGE)
• Formulario: lyophilized
• mol peso: ~80 kDa by SDS-PAGE
• envase: pkg of 50 μg
• condiciones de almacenamiento: avoid repeated freeze/thaw cycles
• impurezas: <0.1 EU/μg endotoxin, tested
• color: white
• Nº de acceso UniProt: O75509
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• Información sobre el gen: human ... TNFRSF21(27242)

Descripción

Descripción general

DR6 is an orphan TNF receptor superfamily member belonging to a subgroup of receptors called death receptors. Expressed ubiquitously with high expression in lymphoid organs, heart, brain, and pancreas. Broadly expressed by developing neurons where it functions as pro-apoptotic factor. Recently, it has been reported that interaction with the beta-amyloid precursor protein (APP) activates a widespread caspase-dependent self-destruction program dependent on caspase-6.

Forma física

Lyophilized from PBS.

Reconstitución

Reconstitute with 50 μL deionized water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.

Otras notas

The Fc portion of human IgG1 is fused to the C-terminus of human DR6 (aa 42-351).

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable