SRP6099

GSTM1 from mouse

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

• Sinónimos: GST 1-1, GST class-mu1, Glutathione S-transferase Mu 1, pmGT10
• UNSPSC Code: 12352200
• NACRES: NA.32

Propiedades

• biological source: mouse
• recombinant: expressed in E. coli
• assay: ≥95% (SDS-PAGE)
• form: liquid
• mol wt: 25.9 kDa
• packaging: pkg of 100 μg
• NCBI accession no.: P10649
• UniProt accession no.: P10649
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: mouse ... GSTM1(14862)

Descripción

General description

GSTM1 (glutathione S-transferase μ 1) belongs to the superfamily of glutathione-S-transferases. It belongs to the μ class of soluble GSTs. GSTM1 is strongly expressed in the kidneys.

Biochem/physiol Actions

Members of GST (glutathione S-transferase) superfamily are responsible for the metabolism of various reactive oxygen species and xenobiotics. GSTM1 (GST μ 1) plays a significant role in vascular homeostasis. Humans with null allele, GSTM1(0), are at increased risks for colon and lung cancers, hypertension, and atherosclerosis, and have higher DNA changes in atherosclerotic lesions of the abdominal aorta.

Physical form

1 mg/mL solution in PBS (pH 7.4) containing 5 mM Glutathione

Preparation Note

Centrifuge the vial prior to opening.

Other Notes

MPMILGYWNV RGLTHPIRML LEYTDSSYDE KRYTMGDAPD FDRSQWLNEK FKLGLDFPNL PYLIDGSHKI TQSNAILRYL ARKHHLDGET EEERIRADIV ENQVMDTRMQ LIMLCYNPDF EKQKPEFLKT IPEKMKLYSE FLGKRPWFAG DKVTYVDFLA YDILDQYRMF EPKCLDAFPN LRDFLARFEG LKKISAYMKS SRYIATPIFS KMAHWSNK

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable